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Michael Krams Selected Research

Therapeutics

3/2015Building a roadmap for developing combination therapies for Alzheimer's disease.
1/2015Charting a path toward combination therapy for Alzheimer's disease.
1/2012Down's syndrome and Alzheimer's disease: towards secondary prevention.
1/2008Missing steps in the STAIR case: a Translational Medicine perspective on the development of NXY-059 for treatment of acute ischemic stroke.
6/2005The past is the future: innovative designs in acute stroke therapy trials.
11/2003Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN): an adaptive dose-response study of UK-279,276 in acute ischemic stroke.

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Michael Krams Research Topics

Disease

10Stroke (Strokes)
01/2021 - 07/2003
4Ischemic Stroke
01/2008 - 11/2003
3Alzheimer Disease (Alzheimer's Disease)
03/2015 - 01/2012
3Infarction (Infarctions)
08/2005 - 07/2003
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
11/2003 - 07/2003
2Infections
11/2003 - 07/2003
1Dementia (Dementias)
01/2012
1Down Syndrome (Down's Syndrome)
01/2012
1Weight Gain
04/2010
1Dissociative Disorders (Fugue)
12/2008
1Major Depressive Disorder (Major Depressive Disorders)
12/2008
1Parkinson Disease (Parkinson's Disease)
10/2008
1Dyskinesias (Dyskinesia)
10/2008
1Amnesia (Dissociative Amnesia)
10/2008
1Parkinsonian Disorders (Parkinsonism)
10/2008
1Embolic Stroke
07/2005
1Neuroinflammatory Diseases
07/2003
1Brain Ischemia (Cerebral Ischemia)
07/2003

Drug/Important Bio-Agent (IBA)

5UK279276IBA
01/2006 - 07/2003
3Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2012
3Glycoproteins (Glycoprotein)IBA
08/2005 - 07/2003
3Neuroprotective AgentsIBA
07/2005 - 07/2003
2traxoprodil mesylateIBA
12/2008 - 10/2008
2N-Methylaspartate (NMDA)IBA
12/2008 - 10/2008
2IntegrinsIBA
07/2005 - 07/2003
2Tissue Plasminogen Activator (Alteplase)FDA Link
11/2003 - 07/2003
1Amyloid (Amyloid Fibrils)IBA
01/2012
1Proteins (Proteins, Gene)FDA Link
01/2012
1Investigational DrugsIBA
04/2010
1Blood Glucose (Blood Sugar)IBA
04/2010
1Antidepressive Agents (Antidepressants)IBA
12/2008
1Excitatory Amino Acid AntagonistsIBA
10/2008
1Levodopa (L Dopa)FDA LinkGeneric
10/2008
1disufenton sodium (NXY 059)IBA
01/2008
1astin AIBA
01/2005
1factor AIBA
07/2003
1FibrinIBA
07/2003

Therapy/Procedure

6Therapeutics
03/2015 - 11/2003
2Thrombolytic Therapy
07/2005 - 07/2003
1Secondary Prevention
01/2012